![]() Last week, one of the biggest players in cell therapy, Kite Pharma, announced it will work with the cancer startup Appia Bio to create breakthrough drugs. Treatments are being developed by two Southern California pharma companies. Kite is based in Los Angeles, CA.The next wave of cancer treatments uses the body's own immune system rather than chemotherapy or radiation to kill cancer cells. In addition, the company is advancing a novel therapeutic cancer vaccine aimed to trigger potent and specific immunity against multiple epithelial cancers, which has the potential to complement its eACT programs. is a privately held development stage biotechnology company engaged in the development of novel cancer immunotherapeutic products, with focus on engineered autologous T cell therapeutics targeted to different tumor types. These encouraging results highlight eACT as an emerging therapeutic modality that could provide new personalized targeted therapy options for cancer patients spanning the spectrum of disease from its early stages to the salvage setting. Clinical studies performed at the National Cancer Institute using these types of engineered peripheral blood T cells have been associated with significant and durable objective clinical responses in cancer patients with advanced metastatic disease, including those with refractory melanoma, sarcoma, lymphoma and leukemia. Belldegrun and Jakobovits to realize the potential of this product platform."Ĭlinical evidence has demonstrated that a patients' peripheral blood T cells, which have been engineered with T cell receptor (TCRs) and Chimeric Antigen Receptors (CARs) that recognize tumor specific molecules, can traffic directly to the tumor, become activated upon engagement with the tumor antigen, and selectively eradicate tumors. "The product pipeline directed to different tumor types, combined with the company's experienced management team, positions Kite to become a leader in this breakthrough therapeutic modality. "Kite's eACT technology has the potential to provide cancer patients with a treatment that offers a significant and durable impact on their disease," said Farah Champsi. "Their experience within the life sciences industry will be valuable to us as Kite enters its next stage of development and growth." "We are pleased to welcome Farah and Ran, who will be adding their expertise to a very active and engaged Board," said Arie Belldegrun. In connection with the financing, Farah Champsi, Managing Director of Alta Partners, and Ran Nussbaum, Managing Partner of Pontifax, have joined Kite's Board of Directors. "The new resources will allow us to advance clinical and manufacturing activities of eACT products directed to hematological and solid tumor indications." "We are extremely pleased with the significant level of interest in Kite and its programs by our existing investors and by Alta Partners, a premier life sciences investment firm," said Aya Jakobovits, Ph.D., President and Chief Executive Officer of Kite Pharma. These novel personalized and targeted immunotherapies, which capitalize on the selectivity and potency of immune cells, are aimed at providing significant and durable clinical benefit regardless of tumor origin, disease stage, and prior treatments. In partnership with the National Cancer Institute (NCI) Surgery Branch under a Cooperative Research and Development Agreement (CRADA), Kite is advancing a pipeline of proprietary eACT product candidates directed at a wide range of cancer indications. Kite is engaged in the development of novel cancer immunotherapeutic products with a focus on engineered autologous T cell therapy (eACT), designed to restore a patient's immune system by recognizing and eradicating tumors. Joined by a new investor, Alta Partners, all existing major investors participated in the financing, including Kite's Founder and Executive Chairman, Arie Belldegrun, M.D., David Bonderman, Pontifax Ltd., Commercial Street Capital, and Michael Milken. KITE PHARMA SERIESIn addition to the $20 million in new funds, Kite converted $15 million in outstanding promissory notes into shares of Series A Preferred Stock. (Kite), a clinical stage biotechnology company focused on developing innovative targeted immunotherapies for cancer, today announced that it has closed a $20 million private placement of shares of its Series A Preferred Stock. LOS ANGELES, /PRNewswire/ - Kite Pharma Inc. ![]()
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